The triple screening test is a test performed to investigate
some chromosomal anomalies that may be in the baby during pregnancy and
congenital anomalies called neural tube defects. As with the Nuchal
translucency scan test, the risk of trisomy 21 (down syndrome) and trisomy 18
(edwards syndrome) is determined in the baby, but does not precisely determine
the presence of these syndromes in the baby. If the risk of these chromosomal
anomalies in the baby is high as a result of the triple test, CVS or
amniocentesis is performed for a definitive diagnosis. B-hCG and free Estriol
(uE3) measurement determine these risks.
Unlike the Nuchal translucency scan test in the triple test,
the risk of anomalies called neural tube defects can also be determined, which
is the AFP (alphafetoprotein) value measured in the triple test. Neural tube
defects are spinal cord injuries related to the baby's nervous system (openness
on the baby's back between the people) or anomalies related to brain injuries.
Trisomy 21 and 18 are diseases with mental retardation, heart
anomalies and many other organ anomalies. That is why these tests are called
intelligence tests, the triple test is not a test that measures the baby's
intelligence level.
The triple test is usually done between 16-20 weeks of
pregnancy, and some laboratories may evaluate between 15-22 weeks. The triple
test is done by taking a small amount of blood from the mother just as in
normal blood tests.
Risk determination according to the end of the triple screening
test is the same as in the double test. (1/270 for Down syndrome, 1/100 for
Edwards syndrome) For detailed information about risk limits, you can read the
double screening test article. In pregnancies with high risk of chromosomal
anomaly as a result of the triple test, the baby may be completely normal, CVS
or amniocentesis is performed to determine the exact result.
Since the risk is high for pregnant women over 35,
amniocentesis is recommended directly without the need for "usually"
triple testing.
How
successful is the triple screening test?
With the triple screening test, not all pregnancies carrying
babies with down syndrome can be determined, but up to 70% can be determined.
In approximately one-third of pregnancies carrying a baby with Down's syndrome,
the triple test result does not come at high risk, it comes normal. It is not
recommended to use the triple test alone due to the low success of this
detection.
- FETAL NUCHAL THICKNESS MEASUREMENT
- NUCHAL TRANSLUCENCY SCAN TEST
- TRIPLE SCAN TEST
- WHAT IS QUADRUPLE BLOOD SCREENİNG TEST?
- INTEGRATED TEST
nuchal translucency scan test
nucheal thickness test in pregnancy
pregnancy test
tests in pregnancy
TRIPLE SCAN TEST
