Cordocentesis is the entry of blood from the umbilical cord
of the baby by entering into the uterus through the abdominal wall with a
special needle during pregnancy. In the cordocentesis process, a small amount
of blood is collected up to 2-3 milliliters.
Karyotyping of the baby, that is, genetic research, can be
performed from the blood taken, as well as to investigate some infections or to
evaluate how the baby is affected by blood incompatibility. If the blood
incompatibility has caused anemia in the baby, blood transfusions can also be
performed to the baby in the womb by the cordocentesis method.
(Abbreviated as PUBS: Percutaneous umbilical cord blood
sampling)
Umbilical vein is preferred for the intervention due to the
large diameter of the umbilical vein (balls vein in the umbilical cord), less
wall thickness and higher incidence of fetal bradycardia in arterial
interventions. First of all, if possible, the entrance area of the cord into
the placenta is preferred. In families with blood incompatibility after
cordocentesis, a blood incompatibility (Anti-D) needle is used.
When is
cordocentesis performed?
Usually 18.-20. It can be done every month from pregnancy
weeks to after birth. Cordocentesis can be applied not only in single pregnancies
but also in twin pregnancies.
In what
situations is cordocentesis applied?
- In case of suspicion of anomaly to the baby in
ultrasonography (this is the most common cause of cordocentesis)
- High risk detected in screening tests
- Other diagnostic methods do not give clear results
- Culture failure in amniocentesis
- Family late application for prenatal diagnosis methods
- In the evaluation of some infectious diseases (toxoplasma,
rubella)
- In the presence of exposure due to blood incompatibility
- In the presence of anemia in the baby
- Advanced maternal age
-Developmental retardation in the uterus in the baby
- Oligohydramnios (low water in the baby)
- In those who gave birth to a baby with an anomaly
- Parental balanced translocation
Cordocentesis leads to more serious complications compared to
other prenatal diagnostic methods. It is a more difficult procedure than
amniocentesis.
What are
the risks of cordocentesis?
Problems such as slowing down, preterm labor, infection, and
umbilical cord injury may be seen after application. Bleeding may occur into
the amniotic fluid. The risk of losing the baby in cordocentesis applications
is about 1-5%. There may be risks such as infection and bleeding related to the
mother. For this reason, it is necessary to urgently consult a doctor in the
presence of fever, chills, chills, vaginal bleeding, pain and contraction in
the days after the procedure.
It is practically not possible for the needle to harm the
baby directly. In other words, there is no such thing as needlestick and injury
of the needle to the baby, because it is observed by observing with ultrasound,
the whole process. However, the risk of deterioration in the baby's heartbeat
and the death of the baby after taking blood from the cord is approximately 1-5
percent.
How is
cordocentesis performed?
The procedure is performed in the supine position with
ultrasound examination. A small amount of blood is taken from the cord with a
needle extended into the uterus by observing the baby and its cord by ultrasound.
It is an average of 10-15 minutes. After the procedure, the patient can rest
for a few hours and go home. The patient is recommended to avoid excessive
strenuous activities for several days after the procedure. If there is a blood
incompatibility between the parents, a needle for a blood incompatibility is
made.
An average week after the procedure, the result becomes clear
and the family is informed according to the result. In cases where chromosomal
anomaly is incompatible with life as a result of cordocentesis, the family is
given the option to terminate pregnancy.
When do the
results of cordocentesis application come out? Is it safe?
After cordocentesis procedure, the result is approximately
7-10 days. Genetic examination processes such as cordocentesis and
amniocentesis give very close results. Conditions such as mother's cells mixed
with blood taken, mosaic in baby can rarely cause misdiagnosis. It can be said
that it gives 99% reliable results in the intended diseases. Not all genetic diseases
can be detected with cordocentesis. After cordocentesis procedure, culture may
not be obtained, in this case, examination cannot be performed.
- FETAL NUCHAL THICKNESS MEASUREMENT
- NUCHAL TRANSLUCENCY SCAN TEST
- TRIPLE SCAN TEST
- WHAT IS QUADRUPLE BLOOD SCREENİNG TEST?
- INTEGRATED TEST
AMINOSYNTHESIS
AMNIUM FLUID MEASUREMENT
false pregnancy
fethal nuchal thickness test
GLUCOSE SCREENİNG TEST
INTEGRATED TEST
QUADRUPLE BLOOD SCREENİNG TEST
TRIPLE SCAN TEST
