Integrated screening test during pregnancy is performed by
performing two tests sequentially.
1) PAPP-A measurement and nuchal thickness (NT) of the baby
are measured between 11-14 weeks. According to these measurements, a risk is
not determined, only the test to be performed later is expected.
2) Quadruple blood screening test is performed between 16-20
weeks and the risk result is determined by integrating with the measurements
specified in the first item.
If the result is determined by measuring NT in the test as
described above, this is called a fully integrated test. If only PAPP-A and
quad test measurements are tested without NT measurement with ultrasound, this
is called serum integrated test.
Integrated test during pregnancy Detecting pregnancies with
Down syndrome is the highest, most reliable test. 92% of babies with Down
syndrome can be determined by a fully integrated test. In serum integrated
testing, this rate is 89%.
According to the integrated test result, the risk of Down
syndrome (trisomy 21) and Edwards syndrome (trisomy 18) in the baby is
determined. If the result is high risk, there is a risk of disease in the baby,
but the baby may be completely normal, so amniocentesis should be performed for
a definitive result. With this test, the risk of neural tube defects can be
determined in the baby since AFP measurement is performed.
Sequential Screening Test: NT and PAPP-A or NT, PAPP-A and
B-HCG are examined between 11-14 weeks. As a result, amniocentesis is
recommended for those at risk of Down syndrome. The risk of Down syndrome is
determined by the integrated test result as above by doing a quad test between
16-20 weeks.
Contingent screening test: Unlike the cascading screening
test, there is no further test on patients with low risk. Amniocentesis is
recommended to the group with high risk as in the step screening test.
Quadruple blood screening test is performed for pregnant women who have
moderate risk after 16-20 weeks.
- BIOPHYSIC PROFILE (BPP)
- INTELLIGENCE TEST IN PREGNANCY
- BIG BABY
- CELL FREE FETAL DNA ANALYSIS (cffDNA)
INTEGRATED TEST
nuchal thickness
nuchal translucency scan test
nucheal thickness test in pregnancy
QUADRUPLE BLOOD SCREENİNG TEST
tests in pregnancy
to be pregnant
TRIPLE SCAN TEST