URINARY TRACT INFECTIONS IN PREGNANCY

A slight growth in kidney size is detected during pregnancy. However, larger changes are increases in the kidney's leaching rate and the amount of blood supply. These changes may also change according to the position of the pregnant woman. In pregnancy, the reabsorption of nutrients from the kidneys decreases, losses occur. A small amount of protein loss can also be detected recently. Urine bleeding may also occur after difficult births.
As the left intestine pushes the uterus to the right, the pressure on the right urinary tract mostly results in enlargement in the right but both kidneys, and the urine waits more and the susceptibility to infections increases. Urinary tract infections are more common in pregnancy. For patients with a history of recurrent urinary tract infection or pyelonephritis, suppressive therapy can be started as soon as pregnancy is detected.
We can examine the urinary tract infection in pregnancy under three headings:
Asymptomatic Bacteriuria (ASB):
It is defined as the presence of bacteria that proliferate in the urine with the absence of signs of infection in the patient. It is diagnosed in the midstream urine culture with more than 100 thousand colonies of bacteria. ASB is associated with low birth weight and preterm birth. The prevalence of ASB varies around 5-7% during pregnancy. If left untreated, ASB can progress to acute pyelonephritis in about 30% of pregnant women. If ASB is treated with appropriate antibiotics, this rate drops to 3%. All women should be screened for bacterial urine at the first examination.
Acute Cystitis:
It occurs in about 1% of pregnant women. Diagnosis of cystitis is based on symptoms of increased urinary frequency, urge to urinate, pain when urinating, bloody urine, pain on the bladder. Acute cystitis bacteriology is the same as asymptomatic bacteriuria and similar treatment is recommended. Acute cystitis is not directly related to the risk of preterm labor, as opposed to asymptomatic bacteriuria and pyelonephritis.
Acute Pyelonephritis:
It is seen in 2% of all pregnancies. Major symptoms are high fever, flank pain, nausea and vomiting. Frequent urination, a sudden urge to urinate, and pain when urinating may be present. The risk of preterm labor and premature rupture of membranes may increase. There are also negative consequences for pregnant women. For example, bacteraemia, sepsis, adult respiratory distress syndrome, and hemolytic anemia. These complications can be seen in pregnant women due to increased sensitivity to bacterial endotoxins and may be life threatening.
Treatment: Must be hospitalized in an emergency hospital, intravenous (intravenous) fluid therapy, antipyretic use and broad-spectrum antibiotics should be given intravenously. Antibiotic therapy should be continued until the patient has spent at least 48 hours without a fever. Antibiotic treatment should be continued as required according to the results of urine culture susceptibility. If there is no change in the findings after 72 hours despite appropriate treatment, antibiotic susceptibility test results and the dose administered should be reviewed and kidney ultrasonography should be performed to detect anatomical anomalies. After the resolution of acute pyelonephritis, the patient should continue antibiotics for a total of 2 weeks and suppressive therapy should continue in the continuation of pregnancy. The recurrence rate is about 20%.

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