CHICKENPOX AND SHINGLES INFECTION IN PREGNANCY

Most people are immune at adult age, as they get this infection in childhood. The "vericella zoster virus", which causes chickenpox infection, remains latent in the body after the infection and becomes active again in the future, creating the disease called shingles. Varicelle virus is a double stranded DNA virus.
Infection of the chickenpox occurs through contact or droplets to infected people. Chickenpox is one of the most contagious infections. It passes 90% to non-immune people in the same environment as someone who had chickenpox. Patients are infectious from one day before the rash to 6-7 days after. Contact with people who have had shingles is also contagious and can cause chickenpox.
The incubation period of the chickenpox is 14 (10-20) days. The day before typical rashes, there may be symptoms such as mild fever, weakness, anorexia. The rash begins first in the form of a pink macule, a red papule appears within a few hours, and immediately afterwards, erythematous vesicles appear. The vesicle wall is thin and soft, easily tears. The clear liquid in it turns cloudy in 12-24 hours, becomes pustule and then crust and poured into brown scales. It does not leave a trace. While the first vesicle disappears, new ones come out in 3-4 days. Thus, all lesions of the chickenpox can be seen simultaneously.
Shingles is usually characterized by painful vesicular lesions and pain in one or more than one adjacent dermatomes (nerve distribution region) in the body.
Diagnosis:
If the mother has positive IgM antibodies or a 4-fold increase in the IgG titer indicates that the new infection has been passed. Only if the IgG is positive, the infection is past because IgM disappears a few months after the infection. People who are both IgM and IgG negative are those who have never encountered this virus and did not get sick and are susceptible to infection because they are not immune, so they must be vaccinated before pregnancy.
Although it is not usually needed for the diagnosis of the disease, virus culture can be made from the fluid in the vesicles.
More information about the diagnosis of the disease in the fetus is not available today.
Effects on the baby during pregnancy:
There is no clear answer to the question whether pregnancy should be terminated when chickenpox is passed during pregnancy. Taking immunoglobulin to the infected mothers can make the disease more mild, but does not prevent the passage to the baby. The infection passes to the baby at rates as low as 1-2%. The majority of babies are not affected by this infection, but especially in babies of those who have had the infection before 20 weeks of gestation, anomalies such as severe brain and nervous system anomalies, eye and skin anomalies, shortness in the legs, weakness in the muscles may occur (congenital vericella infection). Therefore, careful follow-up of pregnancy and detailed ultrasound examinations are required. Mother, father and doctor should make the decision about termination of pregnancy or not.
Shingles infection during pregnancy does not pose a risk for the baby.
Infection, which has a high risk for the baby, is an infection that occurs between 5 days before birth and 2 days after birth. In this case, the chickenpox infection develops at a high rate (20-60%) after birth and death is observed in one third of these babies. Therefore, it is beneficial to delay birth more than 5 days if possible if the mother has an infection in the days close to birth. Immunoglobulin is recommended in the presence of infection during these days close to birth.
Congenital varicella syndrome:
- Chorioretinitis
- Microftalmi
- IUGR
- Skin and bone defects
- Cerebral cortical atrophy

Chickenpox vaccine:
Since chickenpox vaccine is a weakened live vaccine, it cannot be made during pregnancy.
People who are vaccinated against chickenpox are recommended not to become pregnant for 1 month after vaccination and to be protected. However, no abnormality was found in mothers and babies who became pregnant during this period.

-FLU AND UPPER RESPIRATORY INFECTION IN PREGNANCY
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-DYSENTERY AND DIARRHEA IN PREGNANCY
-MUMPS IN PREGNANCY
-MEASLES IN PREGNANCY

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