However, a small portion of these cysts can be associated
with a chromosomal disorder syndrome called trisomy 18 (Edward's syndrome).
However, choroid plexus cyst is not the only symptom of this syndrome. Although
trisomy 18 is most frequently accompanied, more rarely trisomy 21 or trisomy 13
may accompany it. Therefore, patients with choroidal plexus cysts should be
investigated for the presence of other anomalies with detailed ultrasound. In
addition, maternal age, whether there is a chromosomal disease in the family
and triple screening test results should be evaluated. If ultrasound and other
mentioned tests are normal, it is considered to be an isolated (alone) cyst, it
is thought that there will be no chromosomal anomaly and amniocentesis is not
recommended, normal follow-up of pregnancy is continued, no additional
intervention is made.
The size, number and disappearance of these cysts do not change
the risk of trisomy 18. The risk of trisomy 18 is associated with the presence
or absence of other anomalies other than the choroid plexus cyst on ultrasound.
If other anomalies are seen with ultrasound, the diagnosis should be confirmed
with amniocentesis as there may be a high rate of chromosomal anomalies.
ACOG (American College of Obstetricians and Gynecologists) is
recommended by amniocentesis only in the presence of isolated choroid plexus
cyst (when no other anomaly is observed) if the results of triple screening
test are abnormal or if the patient is older than 32 years.
-ANAL ATRESIA
-ANENCEPHALY
-CONGENITAL ANOMALIES
-DOWN SYNDROME (TRISOMY 21)
-ECHOGENIC INTRACARDIAC FOCUS
